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医学摘要翻译(16)

发表时间:2019-1-31  浏览次数:326  
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原文
方法:将120例慢性前列腺炎患者随机分为两组,每组60例,每组又按证候分组为初中期和后期。治疗组初中期以当归浙贝苦参丸合五草汤加减;后期以复元活血汤合(或)桂枝茯苓丸加减。对照组初中期以八正散加减;后期以少府逐瘀汤加减。观察组和对照组均每日1剂,煎取600ml,分两次服用,每次300ml,早晚饭后各一次。两组均以60天为一疗程,一疗程后,对治疗前后慢性前列腺炎症状评分(NIH-CPSI)、前列腺按摩液的变化以及前列腺指诊结果,以及总有效率进行评价。
结果:治疗组总有效率为93.3%,对照组总有效率71.7%,两组疗效比较有显著性差异(P<0.05);治疗组与对照组治疗后NIH-CPSI总分评分均有显著降低,治疗组较对照组NIH-CPSI总分评分差值差异具有统计学意义,治疗组疗效优于对照组(P<0.05)。无论是初中期还是后期,治疗组在改善疼痛程度方面、排尿症状方面、以及改善生活质量方面都优于对照组,差异具有统计学意义(P<0.05)。治疗组在改善前列腺液中白细胞数、卵磷脂小体密度方面优于对照组,差异具有统计学意义(P<0.05)。

译文
Methods: One hundred and twenty patients with chronic prostatitis (C[) were randomly divided into treatment group (n=60) and control group (n=60). Each group was divided into early/middle stage and late stage by syndrome, respectively. For the treatment group, Danggui Zhebei Kushen Pill plus Wucao Decoction was administrated in the early/middle stages (600ml per day, 60 days in total). Patients with late stage CP were given Fuyuan Huoxue Decoction and/or Guizhi Fuling Wan (600ml per day, 60 days in total). In the control group, Bazheng Powder and Shaofu Zhuyu Decoction were given in the early/middle stage and late stage, respectively (600ml per day, 60 days in total). The dosage of the administration was established based on Professor Qi Wang’s sophisticated understanding on TCM including removing blood stasis and dispersing turbidity, treatment by stages, model of differentiation of physique, disease and syndrome. A series of indexes including NIH-Chronic Prostatitis Symptom Index (NIH-CPSI), prostatic secretion, digital prostate examination, and total effective rate were evaluated.
Results: Significant differences were detected in the total effective rates between group and control group (93.3% vs 71.7%, P<0.05). Remarkable decreases of NIH-CPSI were noted in treatment group and control group (P<0.05). Statistical difference was detected in treatment group compared with control group (P<0.05). Remarkable improvements were observed in the pain relief, urination, life quality, amount of white blood cells and density of lecithin body in prostatic fluid of the treatment group compared with control group (P<0.05).
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