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医学翻译样例(10)

发表时间:2019-1-21  浏览次数:144  
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原文:
open-label, randomized trial of rifapentine (Priftin, Sanofi Aventis; 900 mg) plus isoniazid (900 mg) once weekly for 12 weeks (rifapentine–isoniazid), rifampin (600 mg) plus isoniazid (900 mg) twice weekly for 12 weeks (rifampin–isoniazid), isoniazid (300 mg) daily for the duration of the study (≤6 years) (continuous isoniazid),or a control regimen of isoniazid (300 mg) daily for 6 months (6-month isoniazid). All patients received pyridoxine (25 mg) with each dose of antituberculosis medication. Treatment in the rifapentine– isoniazid and rifampin–isoniazid groups was directly observed in the study clinic, whereas in the 6-month–isoniazid and continuous-isoniazid groups, the study drugs were self-administered. Treatment allocation was by a computergenerated algorithm that randomly assigned patients in blocks of 2:2:2:1 to the rifapentine–isoniazid, rifampin–soniazid, 6-month–isoniazid, and continuous-isoniazid groups, respectively.


译文:
随机、开放标签研究:患者随机接受以下治疗方案中的一种:利福喷丁-异烟肼(各900mg),每周一次,共12周;利福平(600mg)-异烟肼(900mg),每周两次,共12周;异烟肼(300mg),每天一次,持续六年;异烟肼(300mg),每天一次,6个月。实施抗结核治疗的患者服用25mg维生素B6。利福喷汀-异烟肼组与利福平-异烟肼组患者直接在研究场所接受临床观察,另外两组(服用异烟肼6个月或持续异烟肼给药组)实施自评,随机化算法由电脑得出,利福喷汀-异烟肼组、利福平-异烟肼组、连续6个月服用异烟肼组及持续异烟肼服用组患者的比例分别为2:2:2:1。

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